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big shtick energy
May 27, 2004


it’s been made optional at work, looks like immediate management has scheduled a meeting in a few hours to clarify how optional it is

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big shtick energy
May 27, 2004


we finally went wfh (still optional technically) on friday, the same day the woman I live with broke up with me. she is on wfh too. we're going to trade off living in the apartment and going to an AirBnB week by week, so if wfh is still optional I might go in to the office during my off week rather than get a proper computer setup in whatever living situation I'm in. she has a more permanent place starting April 1.

apologies in advance if I indirectly kill someone's grandpa by transmitting the virus during all this bullshit.

big shtick energy
May 27, 2004


remote setup is still super annoying for certain things, specifically when you're in embedded and working on devices that cannot be simultaneously connected to in the various ways you need to connect to them

big shtick energy
May 27, 2004


we went from "optional" to "recommended", but management has clarified that this means don't come except for a few minutes to get something or connect something

which is too bad, because I'm getting annoyed with wfh already and was going to just work in an deserted office

big shtick energy
May 27, 2004


thanks to breaking up with my gf and her wanting to rotate sharing our apartment I'm gonna have to work from an AirBnB next week. finding one with a desk that's not an ergonomic nightmare will be tough. probably have to bring my chair from home to make it useable.

big shtick energy
May 27, 2004


President Beep posted:

latest goon saga sounding promising

the best part is she is now at and will be going back to her parents' place when she's not here. so she could be exposing her parents to a lot of risk

big shtick energy
May 27, 2004


Sagebrush posted:

uhhhhhhhhhhhhhh

it’s just for the next few weeks, but yeah, it’s stupid and it sucks

big shtick energy
May 27, 2004


starting coughing this morning, trying not to jump to any conclusions

big shtick energy
May 27, 2004


trip report: had chills last night, not much this morning, but now I'm super fatigued and sore. cough/chest issues are very mild today though

big shtick energy
May 27, 2004


bump_fn posted:

is this poster still alive

i'm fine, unless it gets worse again I think I'm recovering already

big shtick energy
May 27, 2004


my level of panic is like 90 degrees out of phase with the general public. last week I was super worried and getting more worried quickly, while most people didn't give a gently caress yet. now everyone's panic seems to be escalating and personally it now seems like it won't be that bad overall.

big shtick energy
May 27, 2004


i was gonna play the odds and book a vacation for late May, but surprisingly things aren’t super cheap or anything so I guess a lot of people had the same idea

big shtick energy
May 27, 2004


john ionnidis (of "Why Most Published Research Findings Are False" fame) wrote an editorial:

quote:

Early reported CFR figures also seem exaggerated. The most widely quoted CFR has been 3.4%, reported by WHO dividing the number of deaths by the number of documented cases in early march. This ignores undetected infections and the strong age-dependence of CFR. The most complete data come from Diamond Princess passengers, with CFR=1% observed in an elderly cohort; thus, CFR may be much lower than 1% in the general population; probably higher than seasonal flu (CFR=0.1%), but not much so.

Observed crude CFR in South Korea and in Germany, the countries with most extensive testing, is 0.7% and 0.2%, respectively. Even in these countries, many cases probably remain undiagnosed. Therefore, CFR may be even lower.

https://onlinelibrary.wiley.com/doi/abs/10.1111/eci.13222

Other epidemiologists seem to disagree with his outlook, though.

big shtick energy
May 27, 2004


Fatality rate estimate from oxford university:

quote:

Estimating the infection and case fatality ratio for COVID-19 using age-adjusted data from the outbreak on the Diamond Princess cruise ship. Comparing deaths onboard with expected deaths based on naive CFR estimates using China data, they estimated: CFR 1.1% (95% CI: 0.3-2.4%); IFR 0.5% (95% CI: 0.2-1.2%).

Updated: 22nd March: Estimating COVID-19 Case Fatality Rates (CFR) and Infection Rate Fatality (IFR)

The Infection Rate Fatality (IFR) differs from the CFR in that aims to estimate the fatality rate in all those with infection: the detected disease (cases) and those with an undetected disease (asymptomatic and not tested group). if tested, this group would be counted as infected and at least temporarily be immune.

Our current best assumption, as of the 22nd March, is the IFR is approximate 0.19% (95% CI, 0.16 to 0.24).*

In the elderly, co-morbidities have a significant impact on the CFR: those with ≥ 3 comorbidities are at much higher risk, particularly those with cardiovascular conditions. Modelling the data on the prevalence of comorbidities is essential to understand the CFR and IFR by age. In those without pre-existing health conditions, and over 70, the data is reassuring that the IFR will likely not be above 1%. The prevalence of comorbidities is highly age-dependent and is higher in socially deprived.
https://www.cebm.net/global-covid-19-case-fatality-rates/

Unfortunately that's still like 10x a bad flu season, so hospitals are likely to continue being overwhelmed for a while.

big shtick energy
May 27, 2004


FMguru posted:

theyre predicting 40-70% of all people will catch the disease, with a 2-3% death rate

so 1.5% total fatalities sounds about right

117 million deaths worldwide
5.1 million americans
600 thousand californians

it's probably 1/10th of that though

actually that's still a lot

big shtick energy
May 27, 2004


Midjack posted:

I’d like for those numbers to be high but given the quality of response we’ve seen worldwide so far i’m gonna go with them being accurate.

The BMJ published a letter that argues that the widely used numbers are on the high side: https://www.bmj.com/content/368/bmj.m1113

big shtick energy
May 27, 2004


Fabricated posted:

it's cool, trump is very upset about the number going down so its time to sacrifice the poors and olds to try and make it go back up (it will not go back up just because people get forced to go back to work)

stocks did go up today, which is too bad because I meant to do my quarterly buy yesterday but forgot until this morning.

anyway hopefully just a week or two until the data show a clear case for ending lockdowns, but who knows how fast they'll lift after that

big shtick energy
May 27, 2004


quote:

Main results. The actual number of infected cases in France is probably much higher than the observations: we find here a factor x15 (95%-CI: 4-33), which leads to a 5.2/1000 mortality rate (95%-CI: 1.5/1000-11.7/1000) at the end of the observation period. We find a R0 of 4.8, a high value which may be linked to the long viral shedding period of 20 days.

https://www.medrxiv.org/content/10.1101/2020.03.22.20040915v1

These guys got a fatality rate of 0.5%, which is still pretty high, but it's good to see more literature converging toward "this is much more transmissible and much less deadly than we first thought".

big shtick energy
May 27, 2004



lol at getting fired from your doomsday partnership. i wonder what the families think, but I guess they just look at it like a wacky camping trip

big shtick energy
May 27, 2004


my lease is up at the end of may and I don't think they'll accept month to month, so I have like 4 weeks left to give notice of moving out. hoping that the lockdown will be sufficiently lifted by the end of april that i'll be able to look for a new place.

big shtick energy
May 27, 2004


ShadowHawk posted:

The rental and real estate market is taking an absolute dive right now they may be thrilled to have you month to month

true, but I think my ex might just keep living with me until I move out, so I don't really want to extend it. had a brief look on craigslist, and saw at least one place that was doing apartment showings via facetime.

big shtick energy
May 27, 2004


rotor posted:

that seems a little extreme

conferences have been getting more expensive and the alternatives have been getting better. like what might happen with wfh, it could be a big boost to a trend that's already happening

big shtick energy
May 27, 2004


Jonny 290 posted:

I am planning on lockdown through september.

seems unlikely, if 5-10% of people are positive now (iceland mass testing data) it seems likely to peak pretty soon.

big shtick energy
May 27, 2004


Stereotype posted:

The terrifying statistic I heard was that it was still like 10% for people in their 40s. Like, the death rate ramps up to Contagion numbers without ventilators super fast.

no it isn't

anybody who says "the death or hospitalization rate for age group x is y" is talking out of their rear end, because we actually have almost no idea right now. any fraction one can generate where the denominator is the number of people infected is somewhere between a wild-rear end-guess and a vaguely informed estimate

big shtick energy
May 27, 2004


Kazinsal posted:

coronavirus is basically a random chance to get loving murdered by an illness that the world could have stopped from getting to this point. at least if I say the right words then a nazi is going to give me a few seconds to make peace with jesus and accept my fate.

a healthy person has an extremely low chance of having any issues from it, which is why the handful of cases where this happens have gotten a lot of media attention.

big shtick energy
May 27, 2004


first round of data on general population prevalence of antibodies to sars-2-cov

quote:

(April 1, 2020) -- San Miguel County, CO -- San Miguel County Public Health officials announced today that less than 1 percent of the COVID-19 blood tests done last Thursday and Friday were positive for antibodies and 97% of these groups tested negative.

The county appears to include the town of telluride, and not a whole lot else.

big shtick energy
May 27, 2004


ShadowHawk posted:

In some sense we were hoping for the opposite result - that a whole bunch of people had it and developed antibodies/immunity but were asymptomatic.

yes, but it's pretty much the middle of nowhere. results from seattle/bay area/nyc will be a lot more interesting

big shtick energy
May 27, 2004


Welp, a swab test may not find the virus even if you still have it.

https://twitter.com/pdhsu/status/1245406373547933696

big shtick energy
May 27, 2004


a man who takes his usb cables very seriously: https://medium.com/@kolluru.nathan/field-mitigation-of-usb-c-problems-c2024a868760

quote:

In programming terms, you need a mutex/lock. In medical terms, you need incident command authority. If you can obtain neither; abort. You probably can’t afford repercussions in case of fault.

big shtick energy
May 27, 2004


Spain is allegedly had about 15% of the population infected, although most other european countries were at like 3% of the population a week or so ago. More sero-prevelance studies of the US will hopefully come out soon.

I know it has to hit like 80% or something to stop, but presumably it starts to slow down as the people most susceptible to infection (biologically and behaviorally) contract it.

big shtick energy
May 27, 2004


echinopsis posted:

come move to nz and work bleep bloops here



that graph measures disease prevalence in the small subpopulation which has been tested. disease prevalence in the rest of the population is still somewhat unknown but 3-5% of the population as of a week or two ago is a decent estimate.

big shtick energy
May 27, 2004


PIZZA.BAT posted:

youtube just decided to suggest a fox news clip, 'coronavirus may have started in chinese lab according to sources' to me

like as in "some dumbass in a wuhan lab had an oops while studying a cool new virus in pangolins" or as in "BIOLOGICAL ATTACK ON THE AMERICA" because the first one doesn't seem crazy when poo poo like this happens: https://www.cbc.ca/news/canada/manitoba/ebola-henipah-china-1.5232674

big shtick energy
May 27, 2004


power botton posted:

theres so many restrictions and red tape about importing viruses (like there should be) every researcher in smaller labs has smuggled samples and many in larger labs too.

plus we dont need Chinese help doing biological attacks against our own citizens. we used our anthrax very effectively.

that doesn’t make me feel better about anything

big shtick energy
May 27, 2004


the first data from the serological survey from santa clara county is back, they estimated like 3% of the population has had it, but there are some good reasons to think their estimate is high and it could be as low as 1-2%. another study estimated the prevalence at 4% of the population US-wide, 2% excluding new york.

compare that to iceland which had 5% infected already last time I looked, spain that has something like 15%, and the hardest hit parts of italy which are 50% or more. it means the US still has lots of new infections ahead of it.

big shtick energy
May 27, 2004


power botton posted:

it doesn't matter the rates because we cant test for poo poo and dumbshit states/large companies will open up business too quickly with the new federal guidelines and we will spike again.

it seems like to me theres a non zero chance in the summer/fall we'll be dealing with a second wave of corona and 50 or 60% U6 unemployment.

maybe don't jerk it to apocalypse porn ITT where there are lots of people already in a bad state mentally

big shtick energy
May 27, 2004


trump tweeted that all immigration would be temporarily suspended, which it kind of already is since the offices are closed but who knows

the "will I get my green card before bigtech starts doing layoffs" race is gonna be down to the wire

big shtick energy
May 27, 2004


fart simpson posted:

good news. people in south corea and wuhan are already getting it a second time.

maybe, more likely they just have it for a long time and get a negative test at one point because it doesn’t always show up in a throat swab

big shtick energy
May 27, 2004


PIZZA.BAT posted:

yeah back when he was mostly dragging tech companies i was a big fan of his but he's been descending into punditry over the past few years and it's starting to get to the point where it's legitimately blinding him

it's been really disappointing watching his fall

yeah I tried listening to his podcast with kara swisher and it sounded kind of like an AM radio talk show (except with a lot of name dropping by kara)

big shtick energy
May 27, 2004


just thinking out loud here, there's a few ways you could model the purpose and therefore end of lockdowns:

1) most people will get the virus eventually, so lockdowns are in place to "flatten the curve" and avoid overwhelming health care systems. in this scenario it would make sense to start slowly lifting restrictions any place where the health care system has significant excess capacity right now (which is many places in the US). would have to be a slow lift due to the lag in time from exposure to using health care resources

2) longshot jackpot scenario: you can lockdown in your area effectively enough to halt the spread of the virus before most people have had it, and then prevent any new introductions to your area. seems unlikely given the prevalence and asymptomatic spread of the virus, but you could hope for this. probably requires much more stringent lockdowns (national guard delivers your food level) for much longer.

3) longshot jackpot scenario: you can lockdown long enough to develop a highly effective treatment before most people get the virus. of course significant efforts have gone in to looking for treatments for other coronaviruses in the past, but you can hope that with the massive investments being made right now that a highly effective treatment will be found in a few short months.

4) legislators have no idea what the gently caress they are doing and are just sort of charting a course between health experts, perceived public demands, and partisan political goals by the seat of their pants.

i mean obviously scenario 4 is what's happening but I don't really see how 2 and 3 are likely.

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big shtick energy
May 27, 2004


PCjr sidecar posted:

you lock down until you get sufficient testing capacity (actual sero not antibody) to test everyone (ideally multiple times) as well as masks for everyone, get rules around distancing, etc. as well as medical capacity

then you test frequently, temperate checks, rapid response to outbreaks, contract tracing, etc. see South Korea, Taiwan.

how do you scale up the testing to the order of the whole population every couple of days? remember, like half or more of the infectious people will have no symptoms and won't have an elevated temperature.

test-trace-isolate makes sense if you have a thousands infections. I don't see how it can scale to the millions of infections we have now in the united states.

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