[COVIDelta-19] Remember To Mask Up Between Bites

The Something Awful Forums > Discussion > C-SPAM > [COVIDelta-19] Remember To Mask Up Between Bites

shackleford: Sep 4, 2006

Nothus posted:

The only thing making businesses and governments even attempt control measures right now is the fear of litigation. As soon as any kind of virus-related immunity passes, the suffering and death will be entirely within acceptable bounds.

http://www.legis.ga.gov/Legislation/en-US/display/20192020/HB/167

http://www.legis.ga.gov/legislation/en-US/Display/20192020/HB/216

the version that the georgia senate passed (HB 167) has protection against liability for gross negligence (for non-healthcare entities).

quote:

(b) No cause of action shall exist for any transmission of, contraction of, or exposure to COVID-19 unless such transmission, contraction, or exposure was caused by an act or omission constituting willful and wanton misconduct or intentional infliction of harm.

lol

# ¿ Jun 25, 2020 09:13

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# ¿ Apr 25, 2024 01:35

shackleford: Sep 4, 2006

comedyblissoption posted:

https://twitter.com/newoldtymer/status/1290603423591731201

some pages back but i don't think kemp has even signed this bill

http://www.legis.ga.gov/Legislation/20192020/195211.pdf

quote:

SECTION 5.
This Act shall become effective upon its approval by the Governor or upon its becoming law without such approval or on August 7, 2020, whichever occurs first.

also lol

quote:

(2) An individual or entity of the premises has posted at a point of entry, if present, to the premises, a sign in at least one-inch Arial font placed apart from any other text, a written warning stating the following:

'Warning
Under Georgia law, there is no liability for an injury or death of an individual entering these premises if such injury or death results from the inherent risks of contracting COVID-19. You are assuming this risk by entering these premises.'

# ¿ Aug 5, 2020 09:19

shackleford: Sep 4, 2006

Stunt_enby posted:

vaccines aren't poison, but a vaccine that's been pushed through in less than a year from development to production when every other safe vaccine has taken 2-3 years minimum and that is being developed by a new company (moderna) that hasn't delivered a vaccine yet and that has had employees trashing it as just being a vehicle to suck up VC, and that isn't going to have the usual trials done to ensure that there aren't negative long-term effects from it and that could potentially interact negatively with an actually safe vaccine released afterwards is going to be a gamble at best.

hi uh could i get some more information on this last part? is it really possible for an early lovely vaccine to block you from being able to take a later better vaccine? like apparently you can take shingrix (>90% effective) after getting zostavax (51% effective) but is that because they had to prove that they're compatible?

shackleford has issued a correction as of 09:28 on Aug 22, 2020

# ¿ Aug 22, 2020 09:25

shackleford: Sep 4, 2006

MorrisBae posted:

We're going to die because Johnson & Johnson sat on their asses for 6 months to make sure their vaccine worked before ramping up production

lol that owns

lmao and J&J already got paid $1B in order to be able to "immediately" ship 100M doses

https://www.govconwire.com/2020/08/johnson-and-johnson-secures-1b-in-federal-vaccine-production-funding/

quote:

Johnson & Johnson (NYSE: JNJ) has received $1B in U.S. government funding for large-scale production of a potential COVID-19 vaccine as part of the White House�s Operation Warp Speed.

The departments of Defense and Health and Human Services agreed to finance fill-finish manufacturing activities for the company's vaccine candidate at U.S.-based locations, HHS said Wednesday.

Production efforts will take place concurrently with clinical trials which, if successful, would pave the way for authorization from the Food and Drug Administration to immediately ship 100M doses for public use.

# ¿ Jan 31, 2021 01:40

shackleford: Sep 4, 2006

this covers asperger's syndrome right?

# ¿ Mar 8, 2021 07:33

shackleford: Sep 4, 2006

https://www.washingtonpost.com/nation/2021/03/13/terry-wright-galveston-bank-mask/

quote:

Confronted Thursday at a Bank of America in Galveston, Terry Wright scoffed at the idea that she could face criminal consequences. �What are you going to do, arrest me?� she said to a police officer, who had just informed her � in an exchange captured on body camera � that if staff told her to leave, she had to comply.

�The law says that I do not have to wear a mask,� Wright insisted, stating incorrectly that she was in a �public place.�

A minute and a half later, Wright was crouched on the floor, hands cuffed behind her back.

# ¿ Mar 14, 2021 20:49

shackleford: Sep 4, 2006

cool

https://www.biorxiv.org/content/10.1101/2021.01.06.425392v3

quote:

The rapid spread of N501Y in the population increases the likelihood for the emergence of the Q498R mutant, which will probably have even higher infectivity. Conversely to Q498R, both the N501Y and E484K mutations established themselves independently, allowing for their rapid in vitro selection and emergence in SARS-CoV-2. This suggests that with the spread of the �British�, �Brazilian�, and �South African� variants, we project that the Q498R mutation will appear in the future, on top of these mutations. The synergism of Q498R with N501Y and E484K increases ACE2 binding by ~50-fold relative to WT. Another mutation projected to follow is N460K, which emerged late in yeast display. These mutations are located in a hyper-variable region of the RBD (Fig. S11), suggesting that their appearance is not constrained.

Infectivity is one concern of the emerging mutations, but equally important is their potential for immune evasion, both from the resistance provided by previous infections of the WT virus, and even more importantly, from vaccination. To evaluate the effect of these RBD mutations on antibody binding, we manually inspected 92 antibody-RBD (nanobody, Spike) structures for clashes, replacing the WT RBD with the new RBD-62 structure, as determined in complex with ACE2 using Cryo-EM. 28 of the antibodies bind outside the RBM and 8 interactions are not affected by the mutations on RBD-62. However, for 56 antibodies the interaction was compromised and for 9 antibodies, major clashes with RBD-62 were identified (Fig. S12). Notably, E484K and Q498R caused most of the observed effects. While E484K is now prevalent, Q498R has not yet been identified in patients.

An intriguing question is whether the spreading of the tighter binding SARS-CoV-2 variants in humans is accidental. From the similarity to yeast display selection, where stringent conditions are used, one may hypothesize that stringent selection is also driving the rapid spread of these mutations. Abundant low-quality face masks may provide one such selection condition, as they reduce viral titer, but not sufficiently. Therefore, higher quality face-masks (N95) should be encouraged, particularly in closed environments.

# ¿ Mar 22, 2021 06:47

shackleford: Sep 4, 2006

Summer Academic Recovery ~~School~~ Academy

https://www.ajc.com/news/atlanta-news/atlanta-aims-to-enroll-the-majority-of-students-in-summer-school/3ODJTTUSTRHODMDAARAUOGIYWA/

quote:

Atlanta aims to enroll 20,000 students in summer school

Thousands of Atlanta students could spend much of their summer break in school as the district plans a $15 million effort to boost reading and math skills due to the pandemic�s disruption of education.

Atlanta Public Schools hopes to enroll an estimated 20,000 students in a four-week program that begins June 2.

If APS reaches that target, it would represent more than half of the 38,000 students who attend district-run schools and change what summer looks like for many. Atlanta�s charter schools are making their own remediation plans for the quarter of APS students who attend those schools.

While all students across all grades can participate, schools are strongly encouraging those who struggled academically before and during the pandemic to sign up.

�This is a very different lift, but one that we know is so needed,� said Chief Academic Officer Yolonda Brown.

Registration for the virtual and in-person Summer Academic Recovery Academy is open through the end of the month.

APS estimates it will spend $13 million in federal stimulus funds on this summer�s effort, the first of a three-year push to extend learning after the traditional school year ends in May.

# ¿ Apr 3, 2021 23:50

shackleford: Sep 4, 2006

lol

# ¿ Apr 18, 2021 22:00

shackleford: Sep 4, 2006

RedQueen posted:

side thought but i wonder who came up with the phrase �vaccine hesitant� because it stuck, but doesn�t actually tell you how many people might change their mind vs how many they know won�t change it

pollster: will you get vaccinated?
American: absolutely never gently caress that you�ll have to kill me first
pollster: ok we�ll file you under �hesitant�

the truly hesitant have steadily declined since the pfizer results were announced in november

the absolutely never gently caress that etc. have been a steady, solid ~1/4 for at least six months

https://civiqs.com/results/coronavirus_vaccine?annotations=true&uncertainty=true&zoomIn=true

# ¿ May 4, 2021 05:21

shackleford: Sep 4, 2006

Lacrosse posted:

Followup question: how did the 1918 pandemic end without a vaccine? Did it just get bad enough it scythed through the population not willing to take precautions until it burned itself out?

it mutated and became less virulent and became the dominant seasonal influenza A strain for the next few decades. lot of natural immunity from asymptomatic infections and surviving it too

the first influenza vaccines were developed during WWII. when the vaccine totally stopped working in 1947 it was discovered that influenza vaccines needed to be updated periodically

the 1957 H2N2 flu pandemic dislodged H1N1 and became the dominant influenza A

the 1968 H3N2 flu pandemic dislodged H2N2 and became the dominant influenza A

then the chinese or maybe the russians defrosted some classic flu from the '50s and set off H1N1 again

probably because they got spooked by the emergence of H1N1 swine flu in the U.S. in 1976 and started researching H1N1 lol

btw pigs probably had H1N1 because we gave it to them back in the 1910's

shackleford has issued a correction as of 00:38 on May 5, 2021

# ¿ May 5, 2021 00:26

shackleford: Sep 4, 2006

https://twitter.com/Brenbash/status/1389253549998100481

# ¿ May 5, 2021 00:40

shackleford: Sep 4, 2006

https://twitter.com/jeneps/status/1389740176059117572

# ¿ May 5, 2021 01:45

shackleford: Sep 4, 2006

etalian posted:

how far can low energy Fauci shift the "success story" goalposts?

# ¿ May 5, 2021 01:54

shackleford: Sep 4, 2006

TheSlutPit posted:

Has there ever been a disease that reached global pandemic levels where this wasn�t the case? I was looking into it recently and couldn�t find any major one that wasn�t either a) allowed to rip through the population until it burned itself out or b) effectively treated through pharmaceutical intervention (vaccines, antibiotics, etc). Obviously if we had achieved containment early on this could have been another SARS 1 but at this point I�m not sure there are any examples of another option historically.

encephalitis lethargica

# ¿ May 5, 2021 02:48

shackleford: Sep 4, 2006

number has been plummeting since january 20th

# ¿ May 15, 2021 06:03

shackleford: Sep 4, 2006

https://twitter.com/atrupar/status/1394371522366787588?s=19

# ¿ May 17, 2021 20:35

shackleford: Sep 4, 2006

https://twitter.com/GovKemp/status/1397897046225522688

https://twitter.com/AnthonyMKreis/status/1398367554448637960

# ¿ May 28, 2021 23:28

shackleford: Sep 4, 2006

look at this fuckin graph

classical 20th century vaccines (MMR etc.) tend to max out at 88�92% coverage

after the menacwy and chickenpox vaccines were added to the childhood vaccination schedule in the mid-2000's it took about 1.5 decades for those vaccines to approach the traditional ~90% coverage level

here's what the graph of the literal slut vaccine looks like using the most favorable metric (>= 1 dose)

lol, lmfao

# ¿ Jun 2, 2021 00:04

shackleford: Sep 4, 2006

https://twitter.com/BriannaWu/status/1400998163968933888

# ¿ Jun 5, 2021 05:53

shackleford: Sep 4, 2006

https://twitter.com/MikeBeauvais/status/1401026078316056578

# ¿ Jun 5, 2021 06:03

shackleford: Sep 4, 2006

presumably all the red states will be doing this shortly

# ¿ Jun 6, 2021 08:29

shackleford: Sep 4, 2006

welp, looks like crackl-ping has been reading the thread

https://twitter.com/DrEricDing/status/1403132659660902400

# ¿ Jun 13, 2021 03:02

shackleford: Sep 4, 2006

https://twitter.com/PowerDNS_Bert/status/1405269216278679554

welp

https://berthub.eu/articles/posts/curevac-vaccine-and-wonders-of-biology/

quote:

Unlike BioNTech and Moderna, the CureVac SARS-CoV-2 vaccine candidate CVnCoV (aka �zorecimeran�) uses unmodified mRNA, claiming such modifications are not necessary, or even helpful.

I wondered a bit about this and happened to chance on CureVac�s founder Ingmar Hoerr on Linkedin, so I asked him. He responded in public (which is very nice of him):

quote:
�For what reason you should have chemical modifications? This makes sense for gene expression for proteins avoiding immune responses as published by Kariko and Weismann. In terms of vaccines I am not convinced to have these modifications�

i think this is referring to the pseudouridine that is used in pfizer/moderna

https://en.wikipedia.org/wiki/Nucleoside-modified_messenger_RNA

# ¿ Jun 16, 2021 23:33

shackleford: Sep 4, 2006

Asproigerosis posted:

When I got my current job, HR demanded to see my social security card. I didn't have it on me because nobody got around to sending me the info on what to bring to the new hire. I live an hour away so I was just like can I just send you a pic or fax or something? No we need to physically see it! So stupid, you already ring me up on all those databases and background checks for a health care job, why the gently caress do you need to physically see my card in person. A very stupid and pointless 2 hours of driving.

it's the law, but there's also a three day period to get it done. if they made you drive back home on the first day they just did that for fun

https://www.uscis.gov/sites/default/files/document/forms/i-9instr.pdf

quote:

Presenting Form I-9 Documents

Within 3 business days of starting work for pay, you must present to your employer documentation that establishes your identity and employment authorization. For example, if you begin employment on Monday, you must present documentation on or before Thursday of that week. However, if you were hired to work for less than 3 business days, you must present documentation no later than the first day of employment.

[�]

Your employer must review the document(s) you present to complete Form I-9. If your document(s) reasonably appears to be genuine and to relate to you, your employer must accept the documents. If your document(s) does not reasonably appear to be genuine or to relate to you, your employer must reject it and provide you with an opportunity to present other documents from the Lists of Acceptable Documents. Your employer may choose to make copies of your document(s), but must return the original(s) to you. Your employer must review your documents in your physical presence.

you can also present a U.S. passport by itself instead of a driver's license + SSN card

# ¿ Jun 19, 2021 07:55

shackleford: Sep 4, 2006

https://twitter.com/nycsouthpaw/status/1406068384136052739

# ¿ Jun 19, 2021 21:20

shackleford: Sep 4, 2006

Petey posted:

https://twitter.com/EricTopol/status/1405527380618211343

https://twitter.com/allaboutchemist/status/1405531294910476290

Helith posted:

https://twitter.com/abcnews/status/1406517764655775748

Shame we don't have anywhere to actually produce it in Aus if it passes all the clinical trials
ah well, nevertheless

quote:

How is this mRNA vaccine candidate different to Pfizer?

Professor Pouton said the vaccine under development was a "variant vaccine", modelled from the Beta strain, which was first detected in South Africa.

Existing vaccines have been modelled on the original version of the virus first detected in Wuhan.

uh, seems bad to base your vaccine on a much less prevalent variant that's less genetically related to the current dominant strain than the original wuhan wild type?

# ¿ Jun 20, 2021 19:25

shackleford: Sep 4, 2006

hmm seems unlikely that 100% of 75�84 year olds have been vaccinated in georgia

or that 100% of an entire census tract has been vaccinated

# ¿ Jun 27, 2021 18:52

shackleford: Sep 4, 2006

Pingui posted:

Not particularly surprising, but still nice to see someone advising a government saying it:

isn't 90-95% an R0 of 10-20? :monocle:

# ¿ Jul 10, 2021 08:10

shackleford: Sep 4, 2006

https://twitter.com/jlazarus001/status/1424811902010548225

https://twitter.com/jlazarus001/status/1424811904107692034

https://www.usg.edu/regents/members

# ¿ Aug 10, 2021 02:35

shackleford: Sep 4, 2006

https://talkingpointsmemo.com/edblog/are-we-thinking-the-right-way-about-what-constitutes-infection

quote:

As Gandhi tells it, in many cases a vaccinated individual will be exposed to COVID and have the pathogen briefly colonize their nasal passages. But vaccine-induced immunity will fight and defeat the virus there. Is that an infection or a case? If you take a PCR test, you�ll test positive. But Gandhi says we�re confusing things by treating it as one.

i wonder if someone who has a "colonization" (but not an infection) can spread their "colonization" to another individual (who would also not be infected).

also lmao https://twitter.com/ibrake4ants/status/1415701882178314248

# ¿ Aug 11, 2021 00:29

shackleford: Sep 4, 2006

osprey posted:

holy loving poo poo lol

Tests of Cape sewage indicates COVID-19 infections may be far worse than we know

a future variant is gonna cause constipation as a symptom and render wastewater surveillance a useless trailing indicator lol

# ¿ Aug 11, 2021 23:43

shackleford: Sep 4, 2006

https://twitter.com/maddiestone/status/1426004740744245250

# ¿ Aug 13, 2021 07:09

shackleford: Sep 4, 2006

mdemone posted:

hey do we have any earthly idea how effective the mRNA vaccines might be in protecting against the original SARS-CoV-1?

or is that a different enough virus that there's no crossover benefit?

according to paul bieniasz, apparently people with infection + vaccination have mega titers.

https://www.youtube.com/watch?v=LIcaSqQFrX0

vaccinated convalescent plasma neutralizes SARS-CoV-1 (right-most plot) about as well as (non-vaccinated) convalescent plasma neutralizes o.g. wild type (left-most plot):

then they built a doomspike pseudovirus with 20 mutations and found that it basically completely evades convalescent and vaccinee plasma antibodies but vaccinated convalescent plasma still does a good job of neutralizing it:

open question i guess whether 3 doses of mRNA are comparable to WT infection + 2 doses of mRNA

# ¿ Aug 14, 2021 02:16

shackleford: Sep 4, 2006

http://www.english.shamshadnews.com/index.php/afghanistan/77-news/1973-taliban-banned-using-of-covid-19-vaccines-in-paktia

quote:

Taliban Banned Using of COVID-19 Vaccines in Paktia

The armed Taliban banned COVID-19 vaccines in the Paktia regional hospital, provincial Public Health Director, Walayat Khan Ahmadzai said.

According to Ahmadzai, the COVID-19 vaccine ward is closed for the last three days, and the clients are told that the vaccine has been banned.

The Taliban warned the vaccine distribution team to avoid distributing vaccines, Ahmadzai added.

The armed Taliban have not commented on the issue so far.

# ¿ Aug 14, 2021 05:32

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# ¿ Apr 25, 2024 01:35

shackleford: Sep 4, 2006

doing the wrong thing for the right reason

https://www.cnn.com/2021/08/13/us/teacher-parent-fight-face-masks-trnd/index.html

quote:

A California teacher is hospitalized after he's allegedly attacked by a parent over face masks on the first day of school

(CNN) � An elementary school teacher in Northern California was hospitalized after being attacked by a parent during a verbal argument over the use of face masks, the district superintendent said.

The sixth grade teacher was stitched up at the hospital for cuts and lacerations to his face sustained in a physical fight between a parent and the school's principal on the campus of Sutter Creek Elementary School, about 45 miles east of Sacramento, Torie Gibson, Superintendent of Amador County Unified School District told CNN.

"I absolutely will not tolerate violence," Gibson vowed, calling the lack of respect for educators during this pandemic, "baffling."
On Wednesday, the parent arrived about 30-45 minutes after school hours to pick up his daughter who was in the school office with the principal. Both the girl and the principal were wearing face coverings, as mandated by a statewide health order, Gibson said.

According to Gibson, the parent caught a glimpse of several vaccinated educators across the hall in the teachers' lounge not wearing masks and became angry. Teachers are allowed to remove masks in the company of other vaccinated educators, according to a California directive.

After a verbal argument between the student's father and the principal over masks, in which the parent allegedly called the situation a "conspiracy" and claimed children "are being treated like animals," the parent left the campus.

A short time later he returned without his daughter and again engaged in an argument with the principal, Gibson said. When the situation escalated, a male teacher stepped in to try to settle the dad down, but a physical fight ensued.

# ¿ Aug 14, 2021 19:56

The Something Awful Forums > Discussion > C-SPAM > [COVIDelta-19] Remember To Mask Up Between Bites