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I worked on this drug that was a generic antiemetic, but it had to be emulsified in solution. The easiest route to do this was to use poly80, but a lot of people are allergic to poly80, allergic reactions are bad if you are immunocompromised; and more likely than not, if you're being infused with an antiemetic you are severely immunocompromised. This company came up with a novel way of encapsulating the drug in a natural lipid nanoparticle that was hypoallergenic to most people... unless you are allergic to soy or egg. So the base of the compound was anhydrous ethanol, to which was added soybean oil and mixed at temperature until it turned into a substance resembling honey. Then they added the egg white powder. Once all that mixed and basically phase shifted again, they added the drug and then started the extrusion process to create the nanoparticles. I helped a lot with the compound process, but that's real dumbed down because I was a filler, not a compounder. Cut to filling it. The drug looks like cum, but it's thinner than water. All the engineering stuff they did on the pumps was on water, not alcohol, so of course the second it hit the reservoir it started leaking out of the filling nozzles and didn't stop until it was gone. The first couple engineering runs you do with an NPI, you do room holds after the fill is done for 72 hours to simulate the worst-case scenario and see if you actually know how to clean it up. A whole-rear end floor of the building smelled like that poo poo for a straight loving month after we pulled all the congealed, oily mess out of there, 24 hours a day, every loving day. At least it happened on the floor that the supervisor office was on 
MrQwerty fucked around with this message at 09:36 on Oct 17, 2021 |
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Oct 17, 2021 09:33
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| # ¿ Apr 19, 2024 23:33 |
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