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Potato Salad
Oct 23, 2014

nobody cares


"must.....not......fart....."

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NGDBSS
Dec 30, 2009






Isn't that one of the really venomous ones? Some species of blue-ringed octopus?

Beepity Boop
Nov 21, 2012

yay



It is for that guy

Cage Kicker
Feb 20, 2009

End of the fiscal year, bitch.
MP's got time to order pens for year year, hooah?


SKILCRAFT KREW Reppin' Quality Blind Made



Lipstick Apathy
oh god it's even flashing the rings at him

Dirt Road Junglist
Oct 8, 2010

We will be cruel
And through our cruelty
They will know who we are
clench

Stoner Sloth
Apr 2, 2019


:3: what a cutie!

i looked after one of these little guys at a university marine biology department for awhile, cool little critters (his name was George)


NGDBSS posted:

Isn't that one of the really venomous ones? Some species of blue-ringed octopus?

yep - tetrodotoxin is kinda weird too, it's more typical of a poison (not produced by the animal using it, non-protein) rather than a venom but the octopus uses it as both. good example of nature repurposing things. also it's strange how widespread use of ttx is - everything from newts to pufferfish to crabs as well as blue ringed octopus make use of it

Zudgemud
Mar 1, 2009
Grimey Drawer

Stoner Sloth posted:

yep - tetrodotoxin is kinda weird too, it's more typical of a poison (not produced by the animal using it, non-protein) rather than a venom but the octopus uses it as both. good example of nature repurposing things. also it's strange how widespread use of ttx is - everything from newts to pufferfish to crabs as well as blue ringed octopus make use of it

While reading up on it because it sounded cool, it is not really that strange to have it present in that many types of water animals when it is apparently produced by muliple common bacteria found in marine and lake sediment. Especilly when several of the species can colonize/infect sea life and bacteria are so good at horizontal gene transfer.

venus de lmao
Apr 30, 2007

Call me "pixeltits"

The person holding the octopus is almost certainly dead, I think.

Stoner Sloth
Apr 2, 2019

Zudgemud posted:

While reading up on it because it sounded cool, it is not really that strange to have it present in that many types of water animals when it is apparently produced by muliple common bacteria found in marine and lake sediment. Especilly when several of the species can colonize/infect sea life and bacteria are so good at horizontal gene transfer.

Oh it's pretty common for poisons, particularly marine ones - more unusual for it to be used as a venom though.

Admittedly this may be more common than we currently know but still.

BIG HEADLINE
Jun 13, 2006

"Stand back, Ottawan ruffian, or face my lumens!"
I want to assume that's not actually a real Blue-Ringed Octopus and just intricate glass made to look like one.

EDIT: Never mind, it's from that viral TikTok video. Just more proof anyone behind a social media company deserves to go on the Time Machine Kill List.

https://www.thrillist.com/news/nation/tourists-play-with-deadly-blue-ringed-octopus

BIG HEADLINE has a new favorite as of 00:59 on Feb 21, 2021

Frank Dillinger
May 16, 2007
Jawohl mein herr!
Guuuuuuh, that video is making me physically ill.

Grumbletron 4000
Nov 30, 2002

Where you want it, bitch.
College Slice
The best execution method has gotta be this...

https://youtu.be/lfsMMVgIToA

babyeatingpsychopath
Oct 28, 2000
Forum Veteran


OwlFancier posted:

Perhaps some sort of arrangement where you create a sort of nuclear gun barrel capable of containing and directing the blast in a specific direction, and then a sort of nuclear suppressor on the end to absorb and dissipate the energy. Object of your ire goes somewhere in between the two.

Death by gamma knife. I like it. May give 1% of the population we've condemned to death superpowers. Still OK with it.

That or run them through a cobalt chamber. Very Very dead.

ponzicar posted:

They don't want humane executions. They want something that is humane to the executioners, but still causes suffering in the condemned.

And also not be so much of a spectacle that people are "convicted" just so there's something to watch on Execution Thursday every week.

Shifty Nipples
Apr 8, 2007


I thought that was pretty funny fwiw.

Platystemon
Feb 13, 2012

BREADS
The Royal Institution hosted a lecture about the history of nerve agents.

I haven’t watched it yet because it’s an hour long, but it should be right up this thread’s alley.

https://www.youtube.com/watch?v=r7WunS8qCz0

Nebakenezzer
Sep 13, 2005

The Mote in God's Eye

Question about poisons and venom: is it actually possible to build an immunity to some of them?

Phanatic
Mar 13, 2007

Please don't forget that I am an extremely racist idiot who also has terrible opinions about the Culture series.
It’s called mithridatism, it’s real, and overstated. It really only works if you’re talking about something that the immune system can respond to. So yes, there are people who are effectively immune to snake venom due to being bitten so many times, but you cannot give yourself immunity to iocaine powder in this fashion.

The Lone Badger
Sep 24, 2007

You can become resistant to a lot of things. A serious opiate or alcohol addict might take a daily recreational dose that would put a new user on the ground and possibly in the ground.

I think it has sonething to do with receptors, so you can't for example become resistant to cyanide which has a much more direct physiological effect.

Mustached Demon
Nov 12, 2016

A handful of mammals evolved some tolerance to certain venoms. Either through a rigid immune response or the receptors venom goes after have less affinity for the venom. Sort of I guess.

Poisons pretty much depend on what it is. The poison umbrella covers a wide range of chemistries/biologies. They could be larger biomolecules like botulism poop or tiny little guys like HF. Like as long as you use calcium to live you won't build a tolerance to HF.

Rorac
Aug 19, 2011

Nebakenezzer posted:

Question about poisons and venom: is it actually possible to build an immunity to some of them?


The answer to that is "Yes, but only to an extent and only to some things." King Mithridates was paranoid as gently caress and basically took tiny doses of various poisons and slowly amped up the doses to render himself immune. This is where we get "mithridatism" from. That said, poison is in the dosage, and even if you render yourself 'immune' to something, that really only means that you're immune or more accurately resistant, to a conventionally lethal dose.


It doesn't work on everything though. Dose yourself with lead over time, and you don't become immune to lead poisoning, you get lead poisoning.



Hilariously, Mithridates tried to take poison so he wouldn't have the live with the shame of being captured when the enemy came kicking down his doors. Poison that he had rendered himself immune to. He ended up getting an aide to kill him with a sword.

Tunicate
May 15, 2012

Nebakenezzer posted:

Question about poisons and venom: is it actually possible to build an immunity to some of them?

for some things you get more sensitized over time, like poison ivy


on the other hand if you work in a cashew factory for a couple years you can end up immune to poison ivy

Sagebrush
Feb 26, 2012

Phanatic posted:

you cannot give yourself immunity to iocaine powder in this fashion.

We have documentary evidence to the contrary.

Phanatic
Mar 13, 2007

Please don't forget that I am an extremely racist idiot who also has terrible opinions about the Culture series.

Tunicate posted:

for some things you get more sensitized over time, like poison ivy

This can go both ways. Sometimes, like can happen with other allergens, an initial exposure produces no symptoms but sensitizes you and further exposure can trigger a severe reaction. In my case, as a kid I was seriously allergic to the stuff, I swear I could get it if I walked downwind of a plant, and I was constantly being exposed to it. Then in high school I worked for the township cutting grass and trimming back brush, and I just...stopped getting it.

BIG HEADLINE
Jun 13, 2006

"Stand back, Ottawan ruffian, or face my lumens!"
I'm surprised no one's posted it yet, but if you don't like snakes, do not watch this: https://www.youtube.com/watch?v=ucpGlWnq8EE

And yes, to take the surprise out for those who've heard about/seen him before, it's Tim Friede.

More details: https://www.outsideonline.com/2395803/snakebite-antivenom-tim-friede

Eventually his experimentation WILL kill him. You can't take that many bites, especially of the hemotoxic and neurotoxic species, and not EVENTUALLY pay the reaper his due.

BIG HEADLINE has a new favorite as of 05:24 on Feb 26, 2021

Nebakenezzer
Sep 13, 2005

The Mote in God's Eye

^^ fate is a hunter

Ah, that makes sense. Thank you chemfriends

The fact that ancient peoples were convinced it was a thing made me wonder.

ChaseSP
Mar 25, 2013



Some things your body can develop proteins to prevent the toxins/poisons from doing their job as an immune response. But that still requires a frequent low dosage that doesn't end up killing you from it accumulating.

GWBBQ
Jan 2, 2005


Zudgemud posted:

While reading up on it because it sounded cool, it is not really that strange to have it present in that many types of water animals when it is apparently produced by muliple common bacteria found in marine and lake sediment. Especilly when several of the species can colonize/infect sea life and bacteria are so good at horizontal gene transfer.
Yeah, looks like the blue ringed octopus evolved to be resistant to it via a mutation in voltage gated sodium channels, and rather than producing it themselves it's made by bacteria that live in the salivary glands. Looks like there are three amino acid substitutions in the gene for the normally susceptible sodium channel that reduce binding affinity of tetrodoxin.

BIG HEADLINE posted:

I'm surprised no one's posted it yet, but if you don't like snakes, do not watch this: https://www.youtube.com/watch?v=ucpGlWnq8EE

And yes, to take the surprise out for those who've heard about/seen him before, it's Tim Friede.

More details: https://www.outsideonline.com/2395803/snakebite-antivenom-tim-friede

Eventually his experimentation WILL kill him. You can't take that many bites, especially of the hemotoxic and neurotoxic species, and not EVENTUALLY pay the reaper his due.
Don't tell Tim, but usually people wait until after they die to donate their bodies to science.

GWBBQ has a new favorite as of 20:44 on Feb 26, 2021

Zopotantor
Feb 24, 2013

...und ist er drin dann lassen wir ihn niemals wieder raus...

Sagebrush posted:

We have documentary evidence to the contrary.

INCONCEIVABLE!

Zopotantor
Feb 24, 2013

...und ist er drin dann lassen wir ihn niemals wieder raus...

Rorac posted:

Hilariously, Mithridates tried to take poison so he wouldn't have the live with the shame of being captured when the enemy came kicking down his doors. Poison that he had rendered himself immune to. He ended up getting an aide to kill him with a sword.

He died old, though.

El Spamo
Aug 21, 2003

Fuss and misery
Dunno if y'all follow this guy on youtube, but this seems like a particularly appropriate video of his.
Usually Kyle Hill's pretty goofy, but almost all of his nuclear related videos are in tone very serious.

https://www.youtube.com/watch?v=yOdRh5HP650

packetmantis
Feb 26, 2013

Zopotantor posted:

He died old, though.

PYF dangerous chemistry: the cow, the old cow, she is dead

Nebakenezzer
Sep 13, 2005

The Mote in God's Eye

Platystemon posted:

The Royal Institution hosted a lecture about the history of nerve agents.

I haven’t watched it yet because it’s an hour long, but it should be right up this thread’s alley.

https://www.youtube.com/watch?v=r7WunS8qCz0

Just finished watching this, it is good

Tunicate
May 15, 2012

Ibblebibble posted:



Crossover from the anti-food porn thread.

MazeOfTzeentch posted:

That's a username and post combo if I ever saw one :stare:


Ibblebibble posted:

FWIW that was a photoshop by someone in the old just-closed thread, and I didn't notice until it was pointed out :v:

I hope this is a lesson to all of you that there is exactly zero difference between fake things and real things.

https://forums.somethingawful.com/showthread.php?threadid=3766830&userid=178556&perpage=40&pagenumber=10#post512507453

OwlFancier
Aug 22, 2013

The namechange was post-hoc but yes.

BIG HEADLINE
Jun 13, 2006

"Stand back, Ottawan ruffian, or face my lumens!"
If you're swishing mercury around your mouth to let your palate get enough of a "taste" of it, some of its getting into the spaces between your gum and your teeth and thus, into your bloodstream. What an idiot.

I think even back in the day when they had people swallow mercury as a laxative they were smart enough to write something to the effect of "just swallow this poo poo quickly, don't get cute and swish it around your mouth" on the directions.

The Lone Badger
Sep 24, 2007

The mercury you were drinking may have already been through your (or somebody else's) digestive system before. Getting a taste of it is probably not what people wanted to do.

Deteriorata
Feb 6, 2005

BIG HEADLINE posted:

If you're swishing mercury around your mouth to let your palate get enough of a "taste" of it, some of its getting into the spaces between your gum and your teeth and thus, into your bloodstream. What an idiot.

I think even back in the day when they had people swallow mercury as a laxative they were smart enough to write something to the effect of "just swallow this poo poo quickly, don't get cute and swish it around your mouth" on the directions.

Mercury is about the most insoluble substance in bodily fluids that exists. Almost none is going to dissolve directly into your blood or anything else.

The greatest danger of swishing it around is that microglobules of it will get caught between your teeth, where it will slowly evaporate and you will inhale the mercury vapor, thus getting into your body through your lungs. Then it will be running around as a free monotomic atom, where it can be accidentally derivititized into rather toxic organomercury compounds, which will then bioaccumulate in your fat tissues. The vast majority of it will be pooped out as liquid metal.

One exposure will take months to be absorbed. It would take numerous such exposures to amount to a medically noticeable dose. Once stopped, the mercurly would slowly clear the body over the course of several years.

Fuck You And Diebold
Sep 15, 2004

by Athanatos
MSG but the m is mercury

Stoner Sloth
Apr 2, 2019

Deteriorata posted:

Mercury is about the most insoluble substance in bodily fluids that exists. Almost none is going to dissolve directly into your blood or anything else.

The greatest danger of swishing it around is that microglobules of it will get caught between your teeth, where it will slowly evaporate and you will inhale the mercury vapor, thus getting into your body through your lungs. Then it will be running around as a free monotomic atom, where it can be accidentally derivititized into rather toxic organomercury compounds, which will then bioaccumulate in your fat tissues. The vast majority of it will be pooped out as liquid metal.

One exposure will take months to be absorbed. It would take numerous such exposures to amount to a medically noticeable dose. Once stopped, the mercurly would slowly clear the body over the course of several years.

Yeah this is what I'd always heard, if it wasn't inhaled then you can technically drink it "safely" (though you should, of course, never attempt to for the reasons you posted).

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The Lone Badger
Sep 24, 2007

Dimethyl-mercury is the really spicy stuff.

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