|
enraged_camel posted:We have nowhere nearly enough data to determine how frequently covid-19 mutates. How much data do we need and what are you basing that on? We have the full genome of the virus sequenced from 100's of cases. I would of assumed that is enough to determine it quite well?
|
#
?
Mar 28, 2020 23:36
|
|
|
|
| # ? May 31, 2024 03:51 |
|
|
RichardA posted:How much data do we need and what are you basing that on? We have the full genome of the virus sequenced from 100's of cases. I would of assumed that is enough to determine it quite well? Yeah, how do you account for the work being done by Trevor Bedford and his lab at Fred Hutch? https://twitter.com/trvrb/status/1242628550563250176?s=21
|
|
#
?
Mar 28, 2020 23:44
|
|
|
Worker at the local nursing home had the roni. This is gonna suck.
|
|
#
?
Mar 28, 2020 23:44
|
|
|
Koalas March posted:Welp. Got the call that my grandmother is sick. As far as I know she is just experiencing a mild fever and nausea. I'm hoping the nausea means it's something else. My grandma’s got it and still doing ok nearly a week in  be strong.Pure anecdote but most of the people I know who are confirmed (or presumed positive) have noticed a sore throat and then woken up with a fever after a couple days and only then suspected they had it. I don’t see sore throat mentioned much in the expected symptoms so worth keeping in mind for everybody. There’s probably an unfortunate amount of spreading going on because people mainly hone in on fever and cough.
|
|
#
?
Mar 28, 2020 23:44
|
|
|
enraged_camel posted:We have nowhere nearly enough data to determine how frequently covid-19 mutates. Compared to the flu and similar strains, we can know that pretty definitively. The flu is continously mutating all the time. There are two reasons for that. 1: Flu is a wild cocktail of different viruses which are kinda similar. Some are moire dangerous than others, each has a chance to mutate. 2. Each of those "Flu-strains" consists of DNA which is segmented. Basically you have n pieces of DNA, which break apart kinda easily and might reform in one of n! different permutation. The new DNA is mostly the same but the different order confuses antibodies so that they can't detect the new strain. Neither of these points apply to this virus, which implies that mutations are far less likely. Of course regular mutation might still be a thing, but that's a comparatively little change, where big differences are unlikely. Some As will get swapped for some Ts or Gs.
|
|
#
?
Mar 28, 2020 23:52
|
|
|
Ice Phisherman posted:That wasn't some random horny post about how to get your post-apocalyptic girlfriend or boyfriend. It was about how to healthily seek human contact that many of us are going to need in the future because many of us live alone. If I was horny posting I wouldn't for example go out of my way to remind people why you should vet a potential significant other so you don't get stuck with an abuser for months when isolation comes again. horny posting and weird stalker level posting aren't mutually exclusive ah gently caress I forgot to refresh the page before hitting quote this is like 5 pages old lmao Iamgoofball fucked around with this message at 23:55 on Mar 28, 2020 |
|
#
?
Mar 28, 2020 23:53
|
|
|
cant cook creole bream posted:Compared to the flu and similar strains, we can know that pretty definitively. The flu is continously mutating all the time. There are two reasons for that. This thing is far more contagious than the flu, which means a much larger number of hosts. Which means a much greater chance to mutate.
|
|
#
?
Mar 29, 2020 00:00
|
|
|
cant cook creole bream posted:Compared to the flu and similar strains, we can know that pretty definitively. The flu is continously mutating all the time. There are two reasons for that. I mentioned it before, but flus aren't just different species from other flus, some are different GENUSES. Like getting the flu is like getting attacked by a lion on year, then a tiger then next year, then a sea lion the third year. They do mutate, but the fact we get them every year is more about the fact influensa is an extremely broad net of fairly distant viruses. People do end up with some resistance to flus they had even 40 years ago, but it doesn't really matter because we called a really broad set of things influenza and there is always another one to get.
|
|
#
?
Mar 29, 2020 00:00
|
|
|
enraged_camel posted:This thing is far more contagious than the flu, which means a much larger number of hosts. Which means a much greater chance to mutate. The various strains of coronavirus going around causing serious illness (there are 8 right now) haven't really been under any evolutionary pressure because they spread so well. It's a little bit premature to say that coronavirus will maintain it's current, relatively slow mutation rate.
|
|
#
?
Mar 29, 2020 00:06
|
|
|
Guess who got straightened out by their publicist https://www.cnn.com/2020/03/27/entertainment/evangeline-lilly-apology-trnd/index.html
|
|
#
?
Mar 29, 2020 00:06
|
|
|
enraged_camel posted:This thing is far more contagious than the flu, which means a much larger number of hosts. Which means a much greater chance to mutate. Are you sure about that? I know that the "regular flu" (if you could define such a thing) has a way smaller rate of spread. But that doesn't mean it's always this way. There have been flu seasons where pretty much everyone was infected, with incredibly mild symptoms, which just went away after a few days and were barely noticeable. I doubt that corona is spreading wider than every version of influenza in history. Also the factors I mentioned make it way less likely to mutate. In order to level that out by sheer numbers you would need to have hundreds or thosand times the number of infected people. I am pulling these numbers out of my rear end, but if ten times as many people have the corona compared to the flu, the flu is still way way more like to mutate into something else. VVVV Yeah, this too. cant cook creole bream fucked around with this message at 00:16 on Mar 29, 2020 |
|
#
?
Mar 29, 2020 00:13
|
|
|
enraged_camel posted:This thing is far more contagious than the flu, which means a much larger number of hosts. Which means a much greater chance to mutate. Read the twitter thread from the Fred Hutch guy. This one https://mobile.twitter.com/trvrb/status/1242628550563250176 knox_harrington fucked around with this message at 00:17 on Mar 29, 2020 |
|
#
?
Mar 29, 2020 00:15
|
|
|
Man, the one thing about quarantine is this fucks with my sleep schedule hardcore. I'm regularly sleeping like 15-19 hours a night and going to bed at like 9AM. I'm so not excited to get back to an office and classroom lmao
|
|
#
?
Mar 29, 2020 00:17
|
|
|
Spaced God posted:Man, the one thing about quarantine is this fucks with my sleep schedule hardcore. I'm regularly sleeping like 15-19 hours a night and going to bed at like 9AM. I'm so not excited to get back to an office and classroom lmao Use an alarm clock. Seriously, sleeping 19 hours is incredibly unhealthy.
|
|
#
?
Mar 29, 2020 00:18
|
|
|
Dude sleeping 19 hours is a sign of major depression or some other health issue
|
|
#
?
Mar 29, 2020 00:21
|
|
|
Spaced God posted:Man, the one thing about quarantine is this fucks with my sleep schedule hardcore. I'm regularly sleeping like 15-19 hours a night and going to bed at like 9AM. I'm so not excited to get back to an office and classroom lmao The most important thing you can do for yourself is keep on a regular schedule. Get up at a regular time, like 8 AM. Shower, get dressed, leave the bedroom. Go watch TV or YouTube or something. Read a book. Play some games. Do whatever. Don't go back to bed until at least 10 PM, closer to midnight is better. Maintain a routine. It will keep you sane.
|
|
#
?
Mar 29, 2020 00:25
|
|
|
Spaced God posted:Man, the one thing about quarantine is this fucks with my sleep schedule hardcore. I'm regularly sleeping like 15-19 hours a night and going to bed at like 9AM. I'm so not excited to get back to an office and classroom lmao So you go to bed at 9am and then get up again at 4am?
|
|
#
?
Mar 29, 2020 00:25
|
|
|
Sampatrick posted:I enjoy IP's posts even if some of them are a little weird. Yeah, I'll cop to being weird. The world is weird and it's just going to get weirder. What's considered normal is already constantly shifting and it's going to shift radically soon. Some things are going to fundamentally change and we'll have to adapt to a new normal. I can't make any specific predictions. I can only follow trends and look to history for what will emerge from all of this. Some of the predictions I'm making are panning out. Some aren't. But it's important to think about the future. We're entering into entirely unprecedented territory and it's important to start thinking differently about how we approach life to stay ahead. Many of us are going to be in hard isolation until probably June or July because the earliest that I've read that "flattening the curve" happens is May ninth and that's for places that are dealing well with the situation now. Long term isolation is something that most of us have never dealt with before and some of us are straight up not going to cope well or at all with the new normal. And that's just one of many large changes which will feed into many more smaller changes to our way of life. A lot of poo poo is going to change due to the coronavirus and it won't change back. Iamgoofball posted:horny posting and weird stalker level posting aren't mutually exclusive Making sure the person I'm possibly living with when the second wave of coronavirus comes isn't an abuser is important because I'll be stuck with them for months. That's a safety issue and the cops in cities that are hardest hit have flat out told us that they're not going to respond to many crimes because they're going to be busy and I expect for that to become the norm. So if someone starts beating on you or someone else in the house or worse, you're likely on your own. I'd do the same exact thing with a roommate for the exact same reasons. My best friend doesn't have grandparents on one side of his family because his grandfather did a full murder suicide on his entire household, only missing my friend's dad because he was working late that night. There are more firearms sold right now than ever before and you're going to put them into the hands of people who are not going to cope well. Hell loving yes I'm going to vet people before they live with me. I don't need to know every detail of their life, but "will they hurt me" is already important now and it's going to be more pressing after we emerge from all of this. Domestic violence is climbing and it's only going to get higher when people are in a confined space with one another for a long period of time while under stress. People who are in quarantine from now until June or July are not going to do well. Some people who are violent abusers are going to turn even more violent. Some people who were not abusers before will turn into them as they cope in ugly ways. The coming long term isolation is going to traumatize people, even if it is not a total isolation because you can use the phone, text and game with other people. For some people that will be enough. For some it won't. And many people are going to fling themselves into living situations without thinking about who they'll be living with when they emerge from quarantine. Most of us have had that friend who gets into bad relationship after bad relationship because they're lonely. We're all going to emerge from quarantine and some of us will find abusers and then we'll be stuck with them and there will be more abusers than before this hit. But we'll still need people around us because many people will flat out refuse to go through this again for the second wave and the third wave and other waves after that, but we're going to have to anyway. We'll get stuffed back into our homes and without human contact, many people will suffer or even die as a result. Many people won't be able to take going through isolation one more time. And having someone to lean on may make the difference.
|
|
#
?
Mar 29, 2020 00:28
|
|
|
Spaced God posted:Man, the one thing about quarantine is this fucks with my sleep schedule hardcore. I'm regularly sleeping like 15-19 hours a night and going to bed at like 9AM. I'm so not excited to get back to an office and classroom lmao It’s so weird I hear so many people saying things like this because I was unemployed for the first time in like a decade+ for all of December, January, and half of February so these were all things I experienced when the rest of the world was humming along as normal. Imagine how big of a poo poo you feel like when there’s not a global pandemic as an excuse.
|
|
#
?
Mar 29, 2020 00:28
|
|
|
sassassin posted:We should start quarantine areas where no one is allowed in unless they're tested negative or have gone through isolation period. Expand safe zones over time. What if we made it a reverse gulag
|
|
#
?
Mar 29, 2020 00:30
|
|
|
Spaced God posted:Man, the one thing about quarantine is this fucks with my sleep schedule hardcore. I'm regularly sleeping like 15-19 hours a night and going to bed at like 9AM. I'm so not excited to get back to an office and classroom lmao That's really, really bad for you and is a strong sign of depression. You should change your habits so you're not sleeping so much and if that doesn't work, go seek help. If you're having thoughts of self-harm, you should call the national suicide hotline for your country. https://en.wikipedia.org/wiki/List_of_suicide_crisis_lines
|
|
#
?
Mar 29, 2020 00:35
|
|
|
https://www.phila.gov/2020-03-28-where-to-find-free-nutritious-food-during-covid-19/ Philadelphia will begin offering 5-day supplies of food on Mondays and Thursdays. This is in addition to meals being offered to school-aged children (a lot of kids here actually relied on schools for their daily meals).
|
|
#
?
Mar 29, 2020 00:38
|
|
|
Ice Phisherman posted:That's really, really bad for you and is a strong sign of depression. You should change your habits so you're not sleeping so much and if that doesn't work, go seek help. If you're having thoughts of self-harm, you should call the national suicide hotline for your country. I can't believe my mental health got the shortest post I've ever seen out of you, but yeah no I'm already on antidepressants
|
|
#
?
Mar 29, 2020 00:43
|
|
|
Chair In A Basket posted:Worker at the local nursing home had the roni. This is gonna suck. 3 days ago at least 147 nursing homes in the US had at least one affected patient.
|
|
#
?
Mar 29, 2020 00:43
|
|
|
Koalas March posted:Welp. Got the call that my grandmother is sick. As far as I know she is just experiencing a mild fever and nausea. I'm hoping the nausea means it's something else. I’m not sure it’s super well-understood yet overall, but we’ve been taking extreme precautions on all respiratory, febrile and GI symptom patients, and more or less taking baseline droplet precautions on all medical patients otherwise. I think initially GI was reported to be rare but there has been an increasing frequency in GI presentations—although most frequently severe diarrhea (I believe). We are kind of on the initial upswing in SC so I’ve seen a bunch of presumptive cases but nothing yet confirmed. All have been respiratory presentation or just febrile. Our testing regime is total poo poo though.  Just be hopeful. The other less-deadly diseases didn’t take time off. It could just as easily be something else *fingers crossed*
|
|
#
?
Mar 29, 2020 00:45
|
|
|
Spaced God posted:I can't believe my mental health got the shortest post I've ever seen out of you, but yeah no I'm already on antidepressants
|
|
#
?
Mar 29, 2020 00:46
|
|
|
i am harry posted:His posts are why D&D was renamed. Still mad it's not renamed to Survival Sex Havers or something funnier
|
|
#
?
Mar 29, 2020 00:48
|
|
|
Spaced God posted:I can't believe my mental health got the shortest post I've ever seen out of you, but yeah no I'm already on antidepressants Check the side effects. Some anti-depressants, especially if they're new, will cause depression or suicidal thoughts. If they're not new, you should check with your psychiatrist and let them know about your change in behavior and they may adjust your dosage so you're not sleeping 15-19 hours a day. That sort of behavior, again, is a strong indicator of depression. Not certain, but strong. You may have caught your depression early before it gets worse. Please take care of yourself. Also, if you get short on meds, because there's going to be a shortage due to supply chain issues sometime in the near future for literally hundreds of generic meds, check to see what the side effects of coming off your dosage would be or better yet, ask your psychiatrist. Some meds can cause some really nasty side-effects if you come off them without a step-down regimen. They can be life threatening. Ice Phisherman fucked around with this message at 00:53 on Mar 29, 2020 |
|
#
?
Mar 29, 2020 00:50
|
|
|
The Oldest Man posted:Would you be eager to go lick all your friends right after hell virus lockdown was lifted? A few people would but I don't think that's most people. There'd be a ramp up over time. Go around licking people? No.  bars, restaurants, and so forth, creating dense crowds where the virus could easily spread? Yes.mod sassinator posted:This is probably complete lunacy and it's more of a thought exercise, but could you identify antibodies that infected people produced and then CRISPR the generation of those antibodies into everyone's immune systems? Someone's working on a vaccine that works kinda sorta like that. It puts virus genes into your cells, but instead of producing whole entire viruses, the cells just produce the virus surface proteins that your immune system would use for making antibodies.
|
|
#
?
Mar 29, 2020 00:50
|
|
|
Ice Phisherman posted:Check the side effects. Some anti-depressants, especially if they're new, will cause depression or suicidal thoughts. If they're not new, you should check with your psychiatrist and let them know about your change in behavior and they may adjust your dosage so you're not sleeping 15-19 hours a day. wow what don't you act as an authority about
|
|
#
?
Mar 29, 2020 00:51
|
|
|
Spaced God posted:wow what don't you act as an authority about This isn't rocket science. It's depression. It's surprisingly common. A lot of people have had it, including me. I'm also not the only person to ask you to go seek help. People before me told you that what you're going through is not normal. Edit: I'm going to take a break. People aren't happy with me. I'm going to take a week off. Ice Phisherman fucked around with this message at 00:57 on Mar 29, 2020 |
|
#
?
Mar 29, 2020 00:54
|
|
|
Cockmaster posted:Go around licking people? No. Someone hasn't picked their apocalypse harem yet
|
|
#
?
Mar 29, 2020 00:55
|
|
|
Cockmaster posted:Go around licking people? No. It's called survival sex
|
|
#
?
Mar 29, 2020 00:58
|
|
|
Ice Phisherman posted:Check the side effects. Some anti-depressants, especially if they're new, will cause depression or suicidal thoughts. If they're not new, you should check with your psychiatrist and let them know about your change in behavior and they may adjust your dosage so you're not sleeping 15-19 hours a day. That sort of behavior, again, is a strong indicator of depression. Not certain, but strong. You may have caught your depression early before it gets worse. Please take care of yourself. please let the sleepy dude just get some sleep
|
|
#
?
Mar 29, 2020 00:58
|
|
|
Berke Negri posted:please let the sleepy dude just get some sleep Hey man, Stevie Wonder specifically said that sleepers should just stop sleeping.
|
|
#
?
Mar 29, 2020 01:02
|
|
|
I used to go to the gym 4-6 days a week and do cardio on top of that. I can't sleep for poo poo in the new normal of doing sad pushups in the apartment. Last night I layed in bed from like 8pm-midnight, slept a bit, woke up when it was still dark and assumed it must be like 5 or 6am, got in the bath, looked at my phone and realized it was 2am. Meet me halfway, sleepy goon. Like if the rona gets me bad it's gonna be cuz of the sleep deprivation.
|
|
#
?
Mar 29, 2020 01:04
|
|
|
Magic Underwear posted:Wow so glad you came in here to tell us your completely uninformed opinion on a topic which you know nothing about, you loving idiot. Care to elaborate or just talk poo poo? I work in biotech, not personally on mammalian viruses but a lot of my colleagues keep up with all the clinical trials and they aren't optimistic
|
|
#
?
Mar 29, 2020 01:05
|
|
|
I'd been burning the candle at both ends for a while so I'm not ashamed to say I've had a couple 10+ hour nights of sleep. It's not like I can really go do much during the weekend, and it's just me and my dog who has to sleep all day because of heartworm treatment anyway.
|
|
#
?
Mar 29, 2020 01:06
|
|
|
They're saying the USA death toll doubled in 48 hours. That can't be right can it? It's been doubling in 4 days elsewhere. What could explain this?
|
|
#
?
Mar 29, 2020 01:06
|
|
|
|
| # ? May 31, 2024 03:51 |
|
|
After five days of volunteering for 3 to 4 hours a day as the front door people at our local grocery co-op, making sure people wash or sanitize their hands and put on gloves and giving them safety instructions about what to do in the store, and making sure only a small number go inside at a timw, my wife and I both have fevers, lower back pain, exhaustion and sore throats. We took as many precautions as we knew about. So to celestial scribe who asked me not to wonder what happens when all the grocery employees predictably start getting it because that would somehow lead people to not take precautions: go gently caress yourself.
|
|
#
?
Mar 29, 2020 01:06
|
|
